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BIBTEX RIS

Larvicidal activity of vegetable oils and esterified compounds against Culex quinquefasciatus (Diptera: Culicidae)

2017; Elsevier BV; Volume: 143; Linguagem: Inglês

10.1016/j.ecoenv.2017.05.004

ISSN

1090-2414

Autores

José Antônio Ribeiro Neto, Maria Eduarda Amaral Pinto, Vanessa V. Ferreira, Jacqueline Domingues Tibúrcio, Fernando de Pilla Varotti, Dihego Oliveira Azevedo, Ezequias P. Siqueira‐Filho, José Éduardo Serrão, Luciana Alves Rodrigues dos Santos Lima, Stênio Nunes Alves,

Tópico(s)

Malaria Research and Control

Resumo

Control of Culex quinquefasciatus using chemical insecticides may result in the selection of resistant mosquito strains. Thus, the use of plant-derived products has been studied as alternative for the mosquito control. Fatty acid methyl esters (FAMEs) obtained by transesterification of vegetable oils may result in compounds with larvicidal potential against C. quinquefasciatus. However, little is known about the morphological, physiological or biochemical effects that these FAMEs may have on mosquito larvae. The present study reports the effects of these FAMEs in mosquito larvae. The FAMEs were obtained by transesterification of canola, corn, sunflower, and soybean oils with acid catalysis and the determination of FAMEs composition was done by gas chromatography-mass spectrometry (GC-MS). Larvae of C. quinquefasciatus were exposed to different concentrations of the vegetable oils and FAMEs. Thereby, different FAMEs showed LC50 values ranging from 42.32 to 196.27 mg/L against C. quinquefasciatus larvae. The methyl ester obtained from sunflower oil showed the lowest LC50. Histology of C. quinquefasciatus larvae exposed to LC50 of FAMEs was performed and changes in the midgut and fat body morphology were identified. Therefore, larval mortality and changes in the internal organs suggested that FAMEs might be a promising new class of larvicidalcompounds. Cytotoxicity of FAMEs compounds was assessed with the HeLa human cell line and no effect was observed.

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