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Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations

2017; American Association for Cancer Research; Volume: 7; Issue: 9 Linguagem: Inglês

10.1158/2159-8290.cd-16-0960

2159-8290

Franklin W. Huang, Juan Miguel Mosquera, Andrea Garofalo, Coyin Oh, Maria B. Baco, Ali Amin‐Mansour, Bokang Rabasha, Samira Bahl, Stephanie A. Mullane, Brian D. Robinson, Saud H. AlDubayan, Francesca Khani, Beerinder Karir, Eejung Kim, Jeremy Chimene-Weiss, Matan Hofree, Alessandro Romanel, Joseph R. Osborne, Jong Wook Kim, Gissou Azabdaftari, Anna Woloszynska‐Read, Karen S. Sfanos, Angelo M. De Marzo, Francesca Demichelis, Stacey Gabriel, Eliezer M. Van Allen, Jill P. Mesirov, Pablo Tamayo, Mark A. Rubin, Isaac J. Powell, Levi A. Garraway,

Cancer Genomics and Diagnostics

African-American men have the highest incidence of and mortality from prostate cancer. Whether a biological basis exists for this disparity remains unclear. Exome sequencing (