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The problem of spontaneous abortion

1958; Elsevier BV; Volume: 75; Issue: 1 Linguagem: Inglês

10.1016/0002-9378(58)90549-0

1097-6868

J.D. Gray, Carl Tupper, Jessica Rowse,

Reproductive Health and Technologies

The sera of 94 women were examined by a modified Rose-Waaler and the latex flocculation tests. Forty of the 94 were cases of spontaneous abortion, the rest were controls. Except for those women in the first trimester of pregnancy who subsequently aborted or threatened abortion, the Rose-Waaler and latex flocculation titers in the controls were within normal limits. In 29 of 30 cases of spontaneous abortion showing collagen lesions in the villi, the Rose-Waaler and latex flocculation titers were above normal limits. Five cases of abortion were due to other pathological conditions and for the remaining 5 no cause could be found. Attention has been drawn to the parallelism between rheumatoid arthritis and spontaneous abortion. A hypothesis has been advanced offering a partial explanation for the cause of spontaneous abortion covering the majority of cases.