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Pink nodule on the sole

2017; Elsevier BV; Volume: 76; Issue: 6 Linguagem: Inglês

10.1016/j.jaad.2016.11.026

1097-6787

Anna Carbone, Giovanni Paolino, Carlo Cota, Paolo Piemonte, Pasquale Frascione,

Hedgehog Signaling Pathway Studies

A 59-year-old white woman presented with a 5-year history of an asymptomatic 5-mm × 6-mm pink nodule with a superficial crust on the sole of her left foot (Fig 1). Dermoscopy revealed an amelanotic lesion, with a central yellowish crust, with scattered dotted vessels, surrounded by a chrysalis-like rolled border with hairpin vessels and short fine telangiectasia (Fig 2). Excision of the lesion was performed, with the histology shown in Fig 3. 1.What is the most likely diagnosis? A.Wart B.Eccrine poroma C.Molluscum contagiosum D.Hypomelanotic/amelanotic melanoma E.Basal cell carcinoma 2.In palmoplantar areas, what is the main association with this disorder, found so far? A.Human papillomavirus B.Chronic eczema C.Palmoplantar pits in Gorlin–Goltz syndrome D.Sun exposure E.Pompholyx 3.What is the most suitable treatment option? A.Ingenol mebutate gel B.Imiquimod cream 5% C.Vismodegib D.Surgery E.Cryotherapy Fig 2 View Large Image Figure Viewer Download Hi-res image Fig 3 View Large Image Figure Viewer Download Hi-res image