Revisão Acesso aberto Produção Nacional Revisado por pares

Leishmania enriettii (Muniz & Medina, 1948): A highly diverse parasite is here to stay

2017; Public Library of Science; Volume: 13; Issue: 5 Linguagem: Inglês

10.1371/journal.ppat.1006303

ISSN

1553-7374

Autores

Larissa Ferreira Paranaíba, Lucélia J. Pinheiro, Ana Cláudia Torrecilhas, Diego H. Macedo, Armando Menezes‐Neto, Wagner Luiz Tafuri, Rodrigo Pedro Soares,

Tópico(s)

Trypanosoma species research and implications

Resumo

After L. enriettii discovery in C. porcellus in the 1940s [4], the authors failed to infect monkeys, dogs, and wild guinea pigs (C.aperea).They succeeded in infecting only 1 hamster out of 8 animals, and its lesion was poorly infected [2].This is very likely to occur with wild reservoirs of Leishmania, such as opossums and armadillos, which, in nature, harbor low parasite densities without visible infection.At that time, no molecular approaches were available, opening the possibility of detecting L. enriettii in wild reservoirs other than C. aperea (Fig 1).In spite of that, L. enriettii epidemiological studies involving hosts in Brazil are scarce, and new information on this parasite did not emerge until almost 50 years later.Two infected guinea pigs from the city of Capão Bonito (São Paulo state) and 3 from Campina Grande do Sul (Parana ´state) were found.Species status was confirmed by isoenzyme analysis, with the description of a zymodeme polymorphism in the strains from Parana ´ [5].Those data suggest that L. enriettii seems located in the Southern parts of Brazil, but its presence in other states

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