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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis

2017; American Association for the Advancement of Science; Volume: 9; Issue: 391 Linguagem: Inglês

10.1126/scitranslmed.aaf3962

ISSN

1946-6242

Autores

Keiko Imamura, Yuishin Izumi, Akira Watanabe, Kayoko Tsukita, Knut Woltjen, Takuya Yamamoto, Akitsu Hotta, Takayuki Kondo, Shiho Kitaoka, Akira Ohta, Akito Tanaka, Dai Watanabe, Mitsuya Morita, Hiroshi Takuma, Akira Tamaoka, Tilo Kunath, Selina Wray, Hirokazu Furuya, Takumi Era, Kouki Makioka, Koichi Okamoto, Takao Fujisawa, Hideki Nishitoh, Kengo Homma, Hidenori Ichijo, Jean‐Pierre Julien, Nanako Obata, Masato Hosokawa, Haruhiko Akiyama, Satoshi Kaneko, Takashi Ayaki, Hidefumi Ito, Ryuji Kaji, Ryōsuke Takahashi, Shinya Yamanaka, Haruhisa Inoue,

Tópico(s)

Parkinson's Disease Mechanisms and Treatments

Resumo

Analysis of ALS patient iPSC-derived motor neurons indicates that Src/c-Abl inhibitors may have potential for treating ALS.

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