Diagnostic accuracy of nucleic acid amplification tests (NAATs) in urine for genitourinary tuberculosis: a systematic review and meta-analysis
2017; BioMed Central; Volume: 17; Issue: 1 Linguagem: Inglês
10.1186/s12879-017-2476-8
ISSN1471-2334
AutoresCarlos Altez-Fernandez, Victor Ortiz-Soriano, Majid Mirzazadeh, Luis Zegarra, Carlos Seas, César Ugarte‐Gil,
Tópico(s)Infectious Diseases and Tuberculosis
ResumoGenitourinary tuberculosis is the third most common form of extrapulmonary tuberculosis. Diagnosis is difficult because of unspecific clinical manifestations and low accuracy of conventional tests. Unfortunately, the delayed diagnosis impacts the urinary tract severely. Nucleic acid amplification tests yield fast results, and among these, new technologies can also detect drug resistance. There is lack of consensus regarding the use of these tests in genitourinary tuberculosis; we therefore aimed to assess the accuracy of nucleic acid amplification tests in the diagnosis of genitourinary tuberculosis and to evaluate the heterogeneity between studies.
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