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Nanoparticle delivery of curcumin induces cellular hypoxia and ROS-mediated apoptosis via modulation of Bcl-2/Bax in human neuroblastoma

2017; Royal Society of Chemistry; Volume: 9; Issue: 29 Linguagem: Inglês

10.1039/c7nr02770b

2040-3372

Irina Kalashnikova, Joseph Mazar, Craig J. Neal, Amy Rosado, Soumen Das, Tamarah J. Westmoreland, Sudipta Seal,

RNA Interference and Gene Delivery

In this study, several formulations of nanoceria and dextran-nanoceria with curcumin, each demonstrated to have anti-cancer properties, were synthesized and applied as treatment for human childhood neuroblastoma.