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Selenium‐Doped Carbon Quantum Dots for Free‐Radical Scavenging

2017; Wiley; Volume: 56; Issue: 33 Linguagem: Inglês

10.1002/anie.201705989

1521-3773

Feng Li, Tianyu Li, Chenxing Sun, Jiahao Xia, Yang Jiao, Huaping Xu,

Selenium in Biological Systems

Heteroatom doping is an effective way to adjust the fluorescent properties of carbon quantum dots. However, selenium-doped carbon dots have rarely been reported, even though selenium has unique chemical properties such as redox-responsive properties owing to its special electronegativity. Herein, a facile and high-output strategy to fabricate selenium-doped carbon quantum dots (Se-CQDs) with green fluorescence (quantum yield 7.6 %) is developed through the hydrothermal treatment of selenocystine under mild conditions. Selenium heteroatoms endow the Se-CQDs with redox-dependent reversible fluorescence. Furthermore, free radicals such as .OH can be effectively scavenged by the Se-CQDs. Once Se-CQDs are internalized into cells, harmful high levels of reactive oxygen species (ROS) in the cells are decreased. This property makes the Se-CQDs capable of protecting biosystems from oxidative stress.