The Structures of Rieske and Rieske-Type Proteins
1999; Elsevier BV; Linguagem: Inglês
10.1016/s0898-8838(08)60077-x
ISSN1557-8917
Autores Tópico(s)Metalloenzymes and iron-sulfur proteins
ResumoOver the past few decades, numerous studies of this so-called Rieske protein have tried to unravel the molecular basis of its unusual properties. The understanding of the properties of the Rieske protein provides an insight into the general properties of iron sulfur clusters. The essential feature of Rieske clusters is their novel (His2–Cys2) coordination environment that was first established by magnetic spectroscopy and finally proven by the crystal structure determination. This chapter discusses how the distinct spectroscopic, electrochemical, and functional properties of the Rieske protein are determined by the ligand environment and by the protein structure. The chapter uses the term Rieske protein or cluster for hydroquinone-oxidizing electron transport complexes and Rieske-type protein or cluster for dioxygenases or homologous systems where the Rieske-type cluster does not interact with quinone.
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