Portal de Periódicos da CAPES

Botulinum Toxin Injection for the Treatment of Delayed Gastric Emptying Following Pylorus-Preserving Gastrectomy: an Initial Experience

2017; Volume: 17; Issue: 2 Linguagem: Inglês

10.5230/jgc.2017.17.e18

2093-582X

Jung Hwan Lee, Chan Gyoo Kim, Young–Woo Kim, Il Ju Choi, Jong Yeul Lee, Soo‐Jeong Cho, Young‐Il Kim, Bang Wool Eom, Hong Man Yoon, Keun Won Ryu,

Gastroesophageal reflux and treatments

Purpose: To report our experience of endoscopic botulinum toxin injection in patients who experienced severe delayed gastric emptying after pylorus-preserving gastrectomy (PPG). Materials and Methods:We reviewed the medical records of 6 patients who received the botulinum toxin injection.They presented with severe delayed gastric emptying in the early postoperative period.Endoscopic botulinum toxin was administered as 4 injections of 25-50 IU into each of the 4 quadrants of the prepyloric area.Results: All botulinum toxin injections were successful without any complications, enabling 5 patients to tolerate soft solid diets and one to tolerate a soft fluid diet within 10 days.The endoscopic criteria of 4 patients improved.Symptom recurrence caused 2 patients to undergo repeat injections that were successful.The median follow-up period was 27 months, and all patients could ingest normal regular diets at the last follow-up.Conclusions: Endoscopic botulinum toxin injection is a feasible treatment option for early delayed gastric emptying after PPG.