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Revisão Produção Nacional Revisado por pares

BIBTEX RIS

A Rare Presentation of Primary Breast Carcinoma in the Vulva: A Case Report and Literature Review

2017; Elsevier BV; Volume: 18; Issue: 3 Linguagem: Inglês

10.1016/j.clbc.2017.06.004

1938-0666

André Lopes, Jessica St. Louis, Marcelo Luiz Balancin, Angélica Nogueira-Rodrigues, Luana C.F.F. Silva, Eduardo Paulino, Bianca Silveira Sá, Alexandra Bukowski, Edison Mantovani Barbosa, R. L.R. Costa, Paul E. Goss,

Breast Lesions and Carcinomas

The primitive embryonic milk line, which derives from the ectoderm, extends from the axilla to the groin, including the vulva. It appears during the fifth week of embryonic development and regresses in later stages.1-4 The finding of ectopic mammary gland tissue along this line is unusual, with an estimated incidence of 1% in the general population, 0.22% to 0.6% in white individuals, and 3.5% in African American individuals.5,6 There are reports describing it in up to 6% of the population.5,6 Ectopic mammary gland tissue responds to hormonal stimulation and undergoes the same physiologic and pathologic processes found in the normal breast; however, the development of a mammary gland carcinoma (MGC) in this tissue is an extremely rare event.