Ethnicity, sex, and age are determinants of red blood cell storage and stress hemolysis: results of the REDS-III RBC-Omics study
2017; Elsevier BV; Volume: 1; Issue: 15 Linguagem: Inglês
10.1182/bloodadvances.2017004820
ISSN2473-9537
AutoresTamir Kanias, Marion C. Lanteri, Grier P. Page, Yuelong Guo, Stacy Endres‐Dighe, Mars Stone, Sheila M. Keating, Alan E. Mast, Ritchard G. Cable, Darrell J. Triulzi, Joseph E. Kiss, Edward L. Murphy, Steve Kleinman, Michael P. Busch, Mark T. Gladwin,
Tópico(s)Erythrocyte Function and Pathophysiology
ResumoKey Points Genetic and biological variability in blood donors may impact RBC predisposition to hemolysis during cold storage and after transfusion. Male sex, Asian or African American racial background, and older age (>45 years) are significant modifiers of hemolysis.
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