Artigo Acesso aberto Revisado por pares

Ethnicity, sex, and age are determinants of red blood cell storage and stress hemolysis: results of the REDS-III RBC-Omics study

2017; Elsevier BV; Volume: 1; Issue: 15 Linguagem: Inglês

10.1182/bloodadvances.2017004820

ISSN

2473-9537

Autores

Tamir Kanias, Marion C. Lanteri, Grier P. Page, Yuelong Guo, Stacy Endres‐Dighe, Mars Stone, Sheila M. Keating, Alan E. Mast, Ritchard G. Cable, Darrell J. Triulzi, Joseph E. Kiss, Edward L. Murphy, Steve Kleinman, Michael P. Busch, Mark T. Gladwin,

Tópico(s)

Erythrocyte Function and Pathophysiology

Resumo

Key Points Genetic and biological variability in blood donors may impact RBC predisposition to hemolysis during cold storage and after transfusion. Male sex, Asian or African American racial background, and older age (>45 years) are significant modifiers of hemolysis.

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