Portal de Periódicos da CAPES

Artigo Produção Nacional Revisado por pares

BIBTEX RIS

Influência da lidocaína ou da dextrocetamina pela via intratesticular na anestesia com sevoflurano em cães submetidos à orquiectomia eletiva

2015; UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL; Volume: 43; Issue: 1 Linguagem: Inglês

1679-9216

Lianna Ghisi Gomes, David Ronald Parra Travagin, Thalita Priscila Seabra da Cruz, Paulo Roberto Spiller, D. C. Winter, Maria Thereza Bonfim Ens, Letícia da Cunha Dante, Fabíola Niederauer Flôres, Luciana Dambrósio Guimarães,

Anesthesia and Sedative Agents

Background : Elective orchiectomy is one of the most performed surgeries in the veterinary practice and is considered a moderately painful procedure; thus, the use of balanced anesthesia is a good choice. Local anesthetics have shown to be effective for intratesticular and spermatic cord blocks in several species; however, there have been no reports of the use of dextroketamine with this purpose. The objective of this study was to evaluate cardiovascular and respiratory variables, and analgesia produced by intratesticular block using dextroketamine or lidocaine, as well as to assess post-anesthesia recovery and discharge in dogs subjected to elective orchiectomy under inhalation anesthesia with sevoflurane. Materials, Methods & Results : Sixteen dogs which underwent elective orchiectomy were included in this study. All animals were healthy based on clinical and hematological examinations. The animals were randomly distributed into two groups, in which 2% lidocaine at 1 mg/kg (LG) or 5% dextroketamine at 2.5 mg/kg (KG) were administered by the intratesticular route. In both groups, anesthesia was induced with propofol to effect, and maintained with 1.7 V% sevoflurane diluted in 100% oxygen, administered through a calibrated vaporizer and appropriate anesthetic system based on the animal’s weight, kept under spontaneous ventilation. After induction, 10 min were given for stabilization of exhaled anesthetic concentration before one of the treatments was administered intratesticularly. Five min after administration of the local block, the surgical procedure was performed, which lasted up to 15 min. The parameters evaluated were heart rate (HR), respiratory rate (RR), systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure (MAP), oxygen saturation of hemoglobin (SpO2), end-tidal carbon dioxide partial pressure (EtCO2), end-tidal sevoflurane concentration (EtSevo) in exhaled air, and body temperature (ToC), which were measured before administration of the intratesticular treatment and in specific time points during surgery. Analgesia during surgery, and post-anesthetic recovery and discharge were also assessed. There were no statistically significant differences between time points and groups for the variables evaluated. When evaluating post-anesthetic recovery and discharge, all animals received the grade needed for discharge in the first 15 min of evaluation. Discussion : Balanced anesthesia has proven benefits in veterinary medicine since it reduces cardiovascular and respiratory depression, increases drug potency due to synergism, and enables the reduction of inhalational anesthetic requirement during anesthesia. The results of this study show that there was adequate analgesia during the procedure of elective orchiectomy, considering that the values found during surgery were relatively lower than the baseline values and within physiological limits for the species, even during ligation and transection of the spermatic cord, which are described as the most painful moments of the surgical procedure. Anesthetic recovery and discharge were fast owing to the absence of premedication, no residual effects from local anesthesia, and use of sevoflurane, which has a very low blood-gas solubility coefficient and therefore results in faster recovery rates. Therefore, it was possible to conclude that administration of both lidocaine and dextroketamine via the intratesticular route produced adequate analgesia, cardiovascular and respiratory stability, decreased sevoflurane requirement, and yielded fast anesthetic recovery.