Nanostructured Platform Based on Graphene-polypyrrole Composite for Immunosensor Fabrication
2017; Elsevier BV; Volume: 27; Linguagem: Inglês
10.1016/j.protcy.2017.04.047
ISSN2212-0173
AutoresAndreea Cernat, Mihaela Tertiş, Claudia Nicoleta Păpară, Ede Bodoki, Robert Săndulescu,
Tópico(s)Analytical Chemistry and Sensors
ResumoA hybrid graphene-polypyrrole (PPy) composite-based platform was elaborated by using nanosphere lithography structuration. This platform was further used for the antibody anti-acetaminophen immobilization in order to obtain an immunosensor for selective detection of paracetamol (acetaminophen) by using electrochemical methods. After patterning of the composite layer, the five-fold improvement of electrochemical signal was observed, suggesting that a higher amount of antibody was immobilized. This strategy permitted the ease and controlled immobilization of bioreceptors on the composite graphene-PPy platform and enhanced the sensitivity for paracetamol detection.
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