Acute Granulomatous Interstitial Nephritis – A Rare Case of Sarcoidosis
2017; Volume: 1; Issue: 7 Linguagem: Inglês
10.24087/iam.2017.1.7.216
ISSN2520-5110
AutoresJoão Fonseca, José Eduardo Mateus, Benilde Barbosa, Manuel Teixeira Veríssimo, Armando Carvalho,
Tópico(s)Drug-Induced Adverse Reactions
ResumoSarcoidosis is a systemic granulomatous disease of unknown etiology with a wide range of clinical presentations. Authors describe the case of a 72-year-old man with severe acute renal injury secondary to granulomatous interstitial nephritis. Despite the suggestive renal biopsy, only the exclusion of other granulomatous diseases enabled the definitive diagnosis of renal sarcoidosis. The patient underwent hemodialysis and therapy with prednisolone 1mg/kg/day. His serum creatinine returned to baseline over the following months, with no evidence of residual injury. Sarcoid interstitial nephritis is usually silent, and there are very few reported cases associated with severe acute renal failure.
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