Risk factors for uterine fibroids: reduced risk associated with oral contraceptives
1986; BMJ; Volume: 293; Issue: 6553 Linguagem: Inglês
10.1136/bmj.293.6553.1027-a
ISSN0959-8138
Autores Tópico(s)Uterine Myomas and Treatments
ResumoProfessor Ron K Ross and others claim that oral contraceptive (OC) use reduces the risk of uterine fibroids (9 August p 359). Their study group consisted of white married women who had been taking OCs for at least 5 months before their recruitment during the period 1968-1974. Women who have already been taking the pill for 5 or more months exclude (a) those who for cautionary reasons concerning fibroids were not prescribed OCs in the 1st place and (b) those who were taking OCs but discontinued them before 5 months because of fibroid complications. Virtually every informational paper I have reviewed since the very early 1960s through 1968-1974 when the study group was recruited has contained warnings about the use of OCs in women with fibroids. For example: the opinion of Planned Parenthood Federation of Americas Medical Committee the only contraindication to prescription of orals if preexisting fibromyoma (present in about 20% of women) which may enlarge during their use. In contrast preexisting fibroids were not a contraindication in the controls--women using diaphragms and IUDs. It would seem therefore that by omission of the women who had been taking OCs for less than 5 months the study is based on a selected group and the control cases are not comparable. The study suffers from this major flaw. (full text)
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