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WEGENER’S GRANULOMATOSIS DIAGNOSIS FROM ORAL MANIFESTATIONS: A CASE REPORT

2017; Elsevier BV; Volume: 124; Issue: 2 Linguagem: Inglês

10.1016/j.oooo.2017.05.047

2212-4411

MAÍRA TAVARES DE FARIA, Marília Heffer Cantisano, Fábio Ramôa Pires, Ruth Tramontani Ramos, ANDREZA MARIA OLIVEIRA FILGUEIRAS, Thiago Moreira Pêssoa, Geraldo Oliveira Silva-Júnior,

Sarcoidosis and Beryllium Toxicity Research

Wegener's granulomatosis (WG) is a rare granulomatous disease characterized by the classic triad of necrotizing granulomas affecting respiratory tracts, disseminated vasculitis, and glomerulonephritis. It can also affect other sites, such as the oral cavity. Herein we report a case of WG with first manifestation in the oral cavity. A 19-year-old male patient had shown a general hyperplasic gingival growth, display of a granular surface, spontaneous bleeding; multiple granulomatous and necrotic ulcers, symptomatic and spontaneous bleeding located in multiple sites of oral mucosa. An incisional biopsy led to a diagnosis of WG, which was also confirmed by a c-ANCA reactivity. Nasal and maxillary sinus involvement can also be observed. The treatment received was: prednisone 40 mg in the morning and 20 mg at night. After the lesions had healed significantly, the prednisone dose was lowered on a weekly basis.