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Separate and combined associations of obesity and metabolic health with coronary heart disease: a pan-European case-cohort analysis

2017; Oxford University Press; Volume: 39; Issue: 5 Linguagem: Inglês

10.1093/eurheartj/ehx448

1522-9645

Camille Lassale, Ioanna Tzoulaki, Karel G.M. Moons, Michael Sweeting, Jolanda M.A. Boer, Laura Johnson, José María Huerta, Claudia Agnoli, Heinz Freisling, Elisabete Weiderpass, Patrik Wennberg, Daphne L. van der A, Larraitz Arriola, Vassiliki Benetou, Heiner Boeing, Fabrice Bonnet, Sandra Colorado‐Yohar, Gunnar Engström, Anne Kirstine Eriksen, Pietro Ferrari, Sara Grioni, Matthias Johansson, Rudolf Kaaks, Michail Katsoulis, Verena Katzke, Timothy J. Key, Giuseppe Matullo, Olle Melander, Elena Molina‐Portillo, Concepción Moreno-Iribas, Margareta Norberg, Kim Overvad, Salvatore Panico, J. Ramón Quirós, Calogero Saieva, Guri Skeie, Annika Steffen, Magdalena Stępień, Anne Tjønneland, Antonia Trichopoulou, ­Rosario ­Tumino, Yvonne T. van der Schouw, W. M. Monique Verschuren, Claudia Langenberg, Emanuele Di Angelantonio, Elio Ríboli, Nicholas J. Wareham, John Danesh, Adam S. Butterworth,

Obesity, Physical Activity, Diet

The hypothesis of 'metabolically healthy obesity' implies that, in the absence of metabolic dysfunction, individuals with excess adiposity are not at greater cardiovascular risk. We tested this hypothesis in a large pan-European prospective study.