Portal de Periódicos da CAPES

Carbon-Based Nanobiohybrid Thin Film for Amperometric Glucose Sensing

2017; American Chemical Society; Volume: 3; Issue: 9 Linguagem: Inglês

10.1021/acsbiomaterials.7b00325

2373-9878

Samira Bagheri, Amin TermehYousefi, Negar Mansouri, Arman Amani Babadi, Mohd Sayuti Abd Karim, Nahrizul Adib Kadri,

Conducting polymers and applications

This pioneering study involved the fabrication of a new class of nanohybrid-based electrochemical glucose biosensor. First, three-dimensional (3D) graphene was fabricated as a platform of multiwalled carbon nanotube (MWCNT). Then, it was used to immobilize glucose oxidase (GOD) on nanohybrid thin film via the entrapment technique. The modified glucose biosensor indicated excellent biocatalytic activity toward the glucose measurment with a sensitivity of up to 49.58 μA mM–1 cm–2 and a wide linear dynamic range up to 16 mM. The fabricated biosensor shows an excellent stability of 87.8%, with its current diminishing after 3 months. This facile and simple electrochemical method for glucose monitoring using a modified glassy carbon electrode (GCE) by 3DG-MWCNT-GOD could open new avenues in producing of a inexpensive and sensitive glucose nanobiosensors.