Artigo Acesso aberto Revisado por pares

Smartphone-Powered Electrochemical Dongle for Point-of-Care Monitoring of Blood β-Ketone

2017; American Chemical Society; Volume: 89; Issue: 17 Linguagem: Inglês

10.1021/acs.analchem.7b02531

ISSN

1520-6882

Autores

Jinhong Guo,

Tópico(s)

Electrochemical sensors and biosensors

Resumo

A smartphone-powered medical dongle as a miniaturized electrochemical analyzer associated with an enzymatic β-hydroxybutyrate test strip for accurate characterization of blood ketone in peripheral whole blood at the point-of-care, which is capable of providing critical guidance for the evaluation and treatment of diabetic ketoacidosis (DK) and diabetic ketosis acid (DKA), is reported. The measured results of blood ketone by the medical dongle were compared with the clinical results from a bulky biochemical analyzer, and the analysis showed good agreement. The proposed medical smartphone-powered dongle was demonstrated to be a very promising platform as a miniaturized electrochemical analyzer for point-of-care monitoring of the critical biochemical parameters such as blood ketone and a good solution for mobile health management.

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