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Breast cancer, endometrial cancer, and cardiovascular events in participants who used vaginal estrogen in the Women's Health Initiative Observational Study

2017; Lippincott Williams & Wilkins; Volume: 25; Issue: 1 Linguagem: Inglês

10.1097/gme.0000000000000956

1530-0374

Carolyn Crandall, Kathleen M. Hovey, Chris Andrews, Rowan T. Chlebowski, Marcia L. Stefanick, Dorothy S. Lane, Jan L. Shifren, Chu Chen, Andrew M. Kaunitz, Jane A. Cauley, JoAnn E. Manson,

Cancer Risks and Factors

To determine the association between use of vaginal estrogen and risk of a global index event (GIE), defined as time to first occurrence of coronary heart disease (CHD), invasive breast cancer, stroke, pulmonary embolism, hip fracture, colorectal cancer, endometrial cancer, or death from any cause.