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BIBTEX RIS

Exposure to crack cocaine causes adverse effects on marine mussels Perna perna

2017; Elsevier BV; Volume: 123; Issue: 1-2 Linguagem: Inglês

10.1016/j.marpolbul.2017.08.043

1879-3363

Luciane Alves Maranho, Mayana Karoline Fontes, A.S.S. Kamimura, Caio Rodrigues Nobre, Beatriz Barbosa Moreno, Fábio Hermes Pusceddu, Fernando Sanzi Cortez, Daniel Temponi Lebre, Joyce R. Marques, Denis Moledo de Souza Abessa, Daniel Araki Ribeiro, Camilo Dias Seabra Pereira,

Toxic Organic Pollutants Impact

Our study aimed to evaluate crack cocaine effects in different life stages of the marine mussel Perna perna. For this purpose, fertilization rate, embryo-larval development, lysosomal membrane stability and DNA strand breaks were assessed. Effect concentrations in gametes and in larval development were found after 1 h (IC50 = 23.53 mg·L− 1) and 48 h (IC50 = 16.31 mg·L− 1), respectively. The highest tested concentration showing no acute toxicity (NOEC) was 10 mg·L− 1, while the lowest observed effect concentration (LOEC) was 20 mg·L− 1. NOEC concerning embryo-larval development was 0.625 mg·L− 1, while the LOEC was 1.25 mg·L− 1. Cyto-genotoxic effects were evidenced in mussels exposed to crack cocaine concentrations ranging from 5 to 500 μg·L− 1. Our results report the first data on effects of an illicit drug to marine organisms and should encourage further ecotoxicological studies of these contaminants of emerging concern in coastal ecosystems.