Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL
2017; Royal Society of Chemistry; Volume: 15; Issue: 37 Linguagem: Inglês
10.1039/c7ob02045g
ISSN1477-0539
AutoresTahsin F. Kellici, Μaria V. Chatziathanasiadou, Min‐Sung Lee, Nisar Sayyad, Elena Geromichalou, Eirinaios I. Vrettos, Antonis D. Tsiailanis, Seung‐Wook Chi, George D. Geromichalos, Thomas Mavromoustakos, Andreas G. Tzakos,
Tópico(s)RNA Interference and Gene Delivery
ResumoAnti-apoptotic proteins, like the Bcl-2 family proteins, present an important therapeutic cancer drug target.
Referência(s)