
BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits
2017; Springer Science+Business Media; Volume: 17; Issue: 2 Linguagem: Inglês
10.1007/s11101-017-9532-2
ISSN1572-980X
AutoresAlexey Dudnik, A. Filipa Almeida, Ricardo Andrade, Bárbara Gorziza Ávila, Pilar Bañados, Diane Barbay, Jean-Étienne Bassard, Mounir Benkoulouche, Michael Bott, Adelaide Braga, Dario Breitel, Rex Brennan, Laurent Bulteau, Céline Chanforan, Inês Costa, Rafael S. Costa, Mahdi Doostmohammadi, N. Faria, Chengyong Feng, Armando Fernandes, Patrícia Ferreira, R. Ferro, Alexandre Foito, Sabine Freitag, Gonçalo Garcia, Paula Gaspar, Joana Godinho-Pereira, Björn Hamberger, András Hartmann, Harald Heider, Carolina Jardim, Alice Julien-Laferrière, Nicolai Kallscheuer, Wolfgang Kerbe, Oscar P. Kuipers, Shanshan Li, Nicola Love, Alberto Marchetti-Spaccamela, Jan Marienhagen, Cathie Martin, Arnaud Mary, Vincent Mazurek, Camillo Meinhart, David Méndez Sevillano, Regina Menezes, Michael Næsby, Morten H. H. Nørholm, Finn T. Okkels, Joana Oliveira, Marcel Ottens, Delphine Parrot, Lei Pei, Isabel Rocha, Rita Rosado-Ramos, C. Rousseau, Marie-France Sagot, Cláudia Nunes dos Santos, Markus Schmidt, Т. В. Шеленга, Louise Shepherd, Ana Rita Silva, Marcelo Silva, Olivier Simon, Steen G. Stahlhut, Ana Solopova, Artëm Sorokin, Derek Stewart, Leen Stougie, Shang Su, Vera Thole, О. А. Тихонова, Martin Trick, Philippe Vain, André Veríssimo, Ana Vila-Santa, Susana Vinga, Michael Vogt, Liangsheng Wang, Lijin Wang, Wei Wei, Sandra Youssef, Ana Rute Neves, Jochen Förster,
Tópico(s)Microbial Metabolism and Applications
ResumoBACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms. The project aimed at covering all stages of the discovery and pre-commercialization process, including berry collection, screening and characterization of their bioactive components, identification and functional characterization of the corresponding biosynthetic pathways, and construction of Gram-positive bacterial cell factories producing phenolic compounds. Further activities included optimization of polyphenol extraction methods from bacterial cultures, scale-up of production by fermentation up to pilot scale, as well as societal and economic analyses of the processes. This review article summarizes some of the key findings obtained throughout the duration of the project.
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