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Treatment challenges in and outside a network setting: Soft tissue sarcomas

2017; Elsevier BV; Volume: 45; Issue: 1 Linguagem: Inglês

10.1016/j.ejso.2017.09.015

1532-2157

Sandro Pasquali, Sylvie Bonvalot, Dimitri Tzanis, Paolo G. Casali, Annalisa Trama, Alessandro Gronchi, Monika Hackl, E. Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit K. Leinonen, Michel Velten, Xavier Troussard, Véronique Bouvier, Anne‐Valérie Guizard, Anne–Marie Bouvier, Patrick Arveux, Marc Maynadié, Anne-Sophie Woronoff, Michel Robaszkiewicz, Isabelle Baldi, Alain Monnereau, Brigitte Tretarre, Marc Colonna, F. Molinié, Simona Bara, C. Schvartz, Bénédicte Lapôtre-Ledoux, Pascale Grosclaude, Roland Stabenow, Sabine Luttmann, Alice Nennecke, Jutta Engel, Gabriele Schubert-Fritschle, Jan Heidrich, Bernd Holleczek, Jón G. Jónasson, Kerri M. Clough‐Gorr, Harry Comber, Guido Mazzoleni, Adriano Giacomin, Antonella Sutera Sardo, Alessandro Barchielli, Diego Serraino, Roberta De Angelis, Sandra Mallone, Andrea Tavilla, Daniela Pierannunzio, Silvia Rossi, Mariano Santaquilani, Arnold Knijn, Fabio Pannozzo, Valerio Gennaro, Lucia Benfatto, Paolo Ricci, M. Autelitano, Gianbattista Spagnoli, Mario Fusco, Mario Usala, Francesco Vitale, Maria Michiara, ­Rosario ­Tumino, Lucìa Mangone, Fabio Falcini, Stefano Ferretti, Rosangela Filiberti, Enza Marani, Arturo Iannelli, Flavio Sensi, Silvano Piffer, Maria Gentilini, Anselmo Madeddu, Antonio Ziino, Sergio Maspero, Pina Candela, Fabrizio Stracci, Giovanna Tagliabue, Massimo Rugge, Annalisa Trama, Gemma Gatta, Laura Botta, Riccardo Capocaccia, Santa Pildava, Giedrė Smailytė, Neville Calleja, Tom Børge Johannesen, Jadwiga Rachtan, Stanisław Góźdż, Jerzy Błaszczyk, Kamila Kępska, G. Forjaz de Lacerda, María José Bento, Ana Luísa P. Miranda, Chakameh Safaei Diba, Enrique Almar, Nerea Larrañaga, Arantza López de Munain, Ana Torrella-Ramos, J.M. Díaz García, Rafael Marcos‐Gragera, Maria Josè Sanchez, Carmen Navarro, Diego Salmerón, Conchi Moreno‐Iribas, Jaume Galceran, Marià Carulla, Seyed Mohsen Mousavi, Christine Bouchardy, Silvia M. Ess, Andrea Bordoni, Isabelle Konzelmann, Jem Rashbass, Anna Gavin, David Brewster, Dyfed Huws, Otto Visser, Magdalena Bielska-Lasota, Maja Primic‐Žakelj, Ian Kunkler, E Benhamou,

Cutaneous lymphoproliferative disorders research

Patients with soft tissue sarcoma (STS) experienced better outcomes when treated according to existing clinical practice guidelines either at reference institution or dedicated treatment networks. Despite increasing evidence supporting referral to sarcoma specialised units, up to half of patients are not managed according to guidelines, particularly those in the early stage of their disease requiring surgery. Also, criteria to certify expertise of institutions, such as the treatment volume, are debated and health authorities have only recently started identification of these centres and creation of treatment networks in Europe as well as in several countries. This process have important implications for both patient outcomes and innovation of existing treatment strategies through clinical research, making improvement of clinical pathways a priority for health care authorities. This article will discuss issues with management of patients with STS, such as pathological diagnosis and adherence to guidelines, and the definition of referral centres and networks will be illustrated along with existing experiences and population-based data.