Voltar
Revisão Acesso aberto Revisado por pares
BIBTEX RIS

Aging, Osteocytes, and Mechanotransduction

2017; Springer Science+Business Media; Volume: 15; Issue: 5 Linguagem: Inglês

10.1007/s11914-017-0402-z

ISSN

1544-2241

Autores

Haniyeh Hemmatian, Astrid D. Bakker, Jenneke Klein‐Nulend, Harry van Lenthe,

Tópico(s)

Vitamin D Research Studies

Resumo

The bone is able to adapt its structure to mechanical signals via the bone remodeling process governed by mechanosensitive osteocytes. With aging, an imbalance in bone remodeling results in osteoporosis. In this review, we hypothesized that changes in lacunar morphology underlie the decreased bone mechanoresponsiveness to mechanical loading with aging.

Referência(s)