Portal de Periódicos da CAPES

Maca ( Lepidium meyenii ) as a source of macamides and polysaccharide in combating of oxidative stress and damage in human erythrocytes

2017; Wiley; Volume: 53; Issue: 2 Linguagem: Inglês

10.1111/ijfs.13586

1365-2621

Lianzhu Lin, Jiayi Huang, Dongxiao Sun‐Waterhouse, Mouming Zhao, Kun Zhao, Junjie Que,

Seaweed-derived Bioactive Compounds

Summary Maca is known to be rich in macamides. The objective of this study was to analyse macamide profiles of macas with different colours cultivated in Yunnan, China, and commercial Peru maca by ultra‐high‐performance liquid chromatography–tandem mass spectrometry. The antioxidant activities of water, citric acid and alkali‐extracted polysaccharides from Yunnan and Peru macas were evaluated via DPPH radical scavenging activity, oxygen radical absorbance capacity and erythrocyte haemolysis inhibition effect assays. Six major macamides present in Peru maca were also found dominant in Yunnan maca at comparable concentrations. Maca polysaccharide effectively scavenging DPPH and peroxyl radicals protected the erythrocytes against H 2 O 2 ‐induced haemolysis by inhibition of malondialdehyde (MDA) generation. Citric acid extraction was found the most suitable preparation method for generating heteropolysaccharide with strong antioxidant activity. Black maca cultivated in Yunnan possessing the most abundant macamides and polysaccharide with strong antioxidant activity could be developed as functional foods.