Revisão Acesso aberto Revisado por pares

Principles of plasticity in the developing brain

2017; Wiley; Volume: 59; Issue: 12 Linguagem: Inglês

10.1111/dmcn.13546

ISSN

1469-8749

Autores

Bryan Kolb, Allonna Harker, Robbin Gibb,

Tópico(s)

Child and Adolescent Psychosocial and Emotional Development

Resumo

The developing brain is especially sensitive to a wide range of experiences, showing a remarkable capacity for plastic changes that influence behavioural outcomes throughout the lifetime. We review the principles that regulate this plasticity in development and consider the factors that modulate the developing brain. These include early sensory, motor, and language experience, early stress, caregiver interactions, peer interactions, psychoactive drugs, diet, microbiome, and the immune system. Emphasis is given to changes in behaviour, epigenetics, and neuronal morphology. What this paper adds A discussion of the surprising range of factors influencing brain development Life experiences interact resulting in a phenomenon called metaplasticity

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