Carta Acesso aberto Revisado por pares

Concurrent therapy of chronic lymphocytic leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia utilizing CD19-targeted CAR T-cells

2017; Taylor & Francis; Volume: 59; Issue: 7 Linguagem: Inglês

10.1080/10428194.2017.1390237

ISSN

1042-8194

Autores

Mark B. Geyer, Shwetha Manjunath, Andrew G. Evans, Jae H. Park, Marco L. Davila, Corey Cutler, Xiuyan Wang, Yongzeng Wang, Brigitte Sénéchal, Isabelle Rivière, Michel Sadelain, Jane L. Liesveld, Renier J. Brentjens,

Tópico(s)

CAR-T cell therapy research

Resumo

Chimeric antigen receptors (CARs) are recombinant receptors composed of an antibody-derived extracellular single-chain variable fragment linked to a costimulatory signaling domain combined with the...

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