Concurrent therapy of chronic lymphocytic leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia utilizing CD19-targeted CAR T-cells
2017; Taylor & Francis; Volume: 59; Issue: 7 Linguagem: Inglês
10.1080/10428194.2017.1390237
ISSN1042-8194
AutoresMark B. Geyer, Shwetha Manjunath, Andrew G. Evans, Jae H. Park, Marco L. Davila, Corey Cutler, Xiuyan Wang, Yongzeng Wang, Brigitte Sénéchal, Isabelle Rivière, Michel Sadelain, Jane L. Liesveld, Renier J. Brentjens,
Tópico(s)CAR-T cell therapy research
ResumoChimeric antigen receptors (CARs) are recombinant receptors composed of an antibody-derived extracellular single-chain variable fragment linked to a costimulatory signaling domain combined with the...
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