Artigo Revisado por pares

Studies on Gastric Motility in the Cat

1960; Elsevier BV; Volume: 38; Issue: 2 Linguagem: Inglês

10.1016/s0016-5085(60)80011-x

ISSN

1528-0012

Autores

George Perret, F. H. Hesser,

Tópico(s)

Diet and metabolism studies

Resumo

Studies on the effects of vagectomy and other varieties of neural pathway interruption were undertaken as part of a program to investigate the nervous regulation of gastric motility in cat.Data previously available in this field vary with the method and the experimental animal used. 1 • 2 Information based upon radiographic or direct visualization of gastric movements is unsatisfactory for comparison with that obtained by graphic pressure methods.Gastrostomy or gastric fistula techniques introduce the possibility that trauma to the abdomen, and especially to the stomach, might influence the gastric motility pattern.Anesthetics used to immobilize animals generally suppress or otherwise affect smooth muscle activity, and curarizing agents readily introduce difficulties in dosage regulation complicated by anoxia or other side effects.Hence, prolonged and repeated observations on intragastric pressures obtained by oral intubation of waking animals have been restricted largely to trained dogs or docile rabbits and sheep.s-5We have been able to find no studies on gastric activity recorded graphically before and at various intervals after supradiaphragmatic vagectomy, cervical cord transection, sympatho-splanchnicectomy, or thoracic posterior root ganglionectomy in a waking, unanesthetized cat, an animal frequently used in neurophysiologic procedure. MethodsHealthy, adult cats weighing 2.5 to 3.5 kg. were used.Bulbocapnine (50 mg.), supplied by

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