Portal de Periódicos da CAPES

Immunology of Gut-Bone Signaling

2017; Springer Nature; Linguagem: Inglês

10.1007/978-3-319-66653-2_5

2214-8019

Fraser L. Collins, Jonathan D. Schepper, Naiomy D. Rios‐Arce, Michael D. Steury, Ho Jun Kang, Heather Mallin, Daniel Schoenherr, Glen Camfield, Saima Chishti, Laura R. McCabe, Narayanan Parameswaran,

Helicobacter pylori-related gastroenterology studies

In recent years a link between the gastrointestinal tract and bone health has started to gain significant attention. Dysbiosis of the intestinal microbiota has been linked to the pathology of a number of diseases which are associated with bone loss. In addition modulation of the intestinal microbiota with probiotic bacteria has revealed to have both beneficial local and systemic effects. In the present chapter, we discuss the intestinal and bone immune systems, explore how intestinal disease affects the immune system, and examine how these pathologic changes could adversely impact bone health.