Co-occurrence of Guillain-Barré Syndrome and Acute Disseminated Encephalomyelitis with Dual Positive of Anti-GT1a and Anti-GM1 Antibodies
2017; Korean Neurological Association; Volume: 35; Issue: 4 Linguagem: Inglês
10.17340/jkna.2017.4.5
ISSN2288-985X
AutoresJu‐Young Lee, Jinhyuk Yoo, Dong-gook Kang, Yerim Kim, Byeol A Yoon, Jong Kuk Kim, Jong Seok Bae,
Tópico(s)Autoimmune Neurological Disorders and Treatments
ResumoAcute disseminated encephalomyelitis (ADEM) and Guillain-Barré syndrome (GBS) are both rare post-infectious neurological disorders. The co-existence of these conditions has often been reported despite of low incidence. We describe a 20-year-old male, who presented with acute flaccid paralysis and encephalopathy. The patient showed reversible MRI lesions suggesting ADEM. This case showed anti-GT1a IgG and anti-GM1 IgM antibodies positivity. We suggest that certain immunogenicity within central and peripheral nervous system may share a common autoimmune process during the disease course. Key Words: Acute disseminated encephalomyelitis, Guillain-Barré syndrome, Gangliosides
Referência(s)