Portal de Periódicos da CAPES

Artigo Produção Nacional Revisado por pares

BIBTEX RIS

Cross-reactivity between Potamotrygon motoro antivenoms and dorsal and stinger extracts of others stingrays (Chondrichthyes: Potamotrygonidae) from the Amazon basin

2017; Taylor & Francis; Volume: 38; Issue: 1 Linguagem: Inglês

10.1080/15569543.2017.1394324

1556-9551

Juliana Luiza Varjão Lameiras, Valéria Mourão de Moura, Lucas Castanhola Dias, Ilia Gilmara Carvalho dos Santos, Oscar Tadeu Ferreira da Costa, Maria Cristina Dos‐Santos,

Marine Invertebrate Physiology and Ecology

In this study, two mouse hyperimmune sera were produced, one using extract from the stinger of the stingray Potamotrygon motoro and the other using extract from the dorsal region of the same species and their cross-reactivity with extracts from the following species of stingrays from the Amazon basin was investigated using Western blot and dot ELISA: Paratrygon aiereba, Plesiotrygon iwamae, Potamotrygon orbignyi and Potamotrygon schroederi. The results show that the dorsal extract was as immunogenic as the stinger extract and induced high levels of antibodies, which reacted with homologous and heterologous antigens, indicating that both types of extract may be suitable for use in the production of antivenom to treat victims of envenomation by stingrays.