Abstract 13794: An Orally-Active Small-Molecule Antagonist of the Platelet Protease-Activated Receptor-4, BMS-986141, Prevents Aeterial Thrombosis With Low Bleeding Liability in Cynomolgus Monkeys
2017; Lippincott Williams & Wilkins; Volume: 136; Linguagem: Inglês
ISSN
1524-4539
AutoresPancras C. Wong, Carol A. Watson, Jeffery Bostwick, Jacques Banville, Ruth R. Wexler, E. Scott Priestley, Anne Marinier, Michel Bouvier, David Gordon, William Schumacher, Jing Yang,
Tópico(s)Venous Thromboembolism Diagnosis and Management
ResumoIntroduction: BMS-986141 (BMS) is a small-molecule platelet thrombin receptor antagonist selective for the protease-activated receptor-4 (PAR4), and is under clinical investigation. Hypothesis: Blo...
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