Portal de Periódicos da CAPES

Saffron against Components of Metabolic Syndrome: Current Status and Prospective

2017; American Chemical Society; Volume: 65; Issue: 50 Linguagem: Inglês

10.1021/acs.jafc.7b03762

1520-5118

Mojtaba Shafiee, Nazanin Sadat Aghili Moghaddam, Mohammad Nosrati‐Oskouie, M. Seilanian Tousi, Amir Avan, Mikhail Ryzhikov, Mohammad Reza Parizadeh, Hamid Fiuji, Majid Rajabian, Amirhossein Bahreyni, Majid Khazaei, Seyed Mahdi Hassanian,

Neurological Disorders and Treatments

Saffron, the dried stigmas of Crocus sativus L., is mainly used as a food coloring and flavoring agent. This agricultural product is used in traditional medicine for the treatment of several diseases including asthma, liver disease, menstruation disorders, and, of special interest in this review, metabolic syndrome. Saffron and its active components including crocin, crocetin, and safranal are potential therapeutic candidates for attenuating MetS complications including hypertension, hyperglycemia, obesity, and dyslipidemia. This review summarizes the protective role of saffron and its constituents in the pathogenesis of MetS for a better understanding and hence a better management of this disease.