Sino‐Nasal outcome test‐22 outcomes after sinus surgery: A systematic review and meta‐analysis
2017; Wiley; Volume: 128; Issue: 3 Linguagem: Inglês
10.1002/lary.27008
ISSN1531-4995
AutoresZachary M. Soler, Rabun Jones, Phong T. Le, Luke Rudmik, José L. Mattos, Shaun A. Nguyen, Rodney J. Schlosser,
Tópico(s)Nasal Surgery and Airway Studies
ResumoObjectives/Hypothesis The goal of the study was to perform a systematic review with meta‐analysis to determine the mean change in the 22‐item Sino‐Nasal Outcome Test (SNOT‐22) across patients who have had endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) in the literature. Methods A literature search was performed to identify studies that assessed SNOT‐22 scores before and after ESS in adult patients with CRS. A random effects model with inverse variance weighting was used to generate the mean change after surgery, along with the forest plot and 95% confidence interval (CI). The impact of patient‐specific factors across studies was assessed using a mixed‐effects meta‐regression. Results The final study list included 40 unique patient cohorts published from 2008 to 2016. All studies showed a statistically significant change in mean SNOT‐22 scores between baseline and postoperative time points ( P < .001), ranging from 12.7 to 44.8, at an average follow‐up of 10.6 months. The summary change in mean SNOT‐22 across all studies was 24.4 (95% CI: 22.0‐26.8). After forward, step‐wise multivariate modeling, studies with higher mean preoperative SNOT‐22 score and higher asthma prevalence were associated with greater changes in SNOT‐22 score after ESS, whereas studies with longer mean follow‐up had smaller changes in SNOT‐22 score. Conclusions Studies evaluating quality‐of‐life outcomes after sinus surgery using the SNOT‐22 instrument universally show significant improvement after ESS. Across the published literature, the magnitude of change is quite variable and appears to be influenced by a number of factors including baseline SNOT‐22 score, asthma prevalence, and length of follow‐up. Laryngoscope , 128:581–592, 2018
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