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Arundinosides A-G, new glucosyloxybenzyl 2 R -benzylmalate derivatives from the aerial parts of Arundina graminifolia

2017; Elsevier BV; Volume: 125; Linguagem: Inglês

10.1016/j.fitote.2017.11.019

1873-6971

Florence Auberon, Opeyemi Joshua Olatunji, Stéphanie Krisa, Gaëtan Herbette, Cyril Antheaume, Frédéric Bonté, Jean‐Michel Mérillon, Annelise Lobstein,

Bioactive natural compounds

Seven new glucosyloxybenzyl 2R-benzylmalate derivatives, arundinosides A-G (1–7) were isolated from the aerial parts of the bamboo orchid Arundina graminifolia. This is the first occurrence of this class of compounds in the genus Arundina. Their planar structures and absolute configuration were determined by extensive NMR spectroscopic data as well as chemical conversion. Their neuroprotective properties were also evaluated on their potential ability to reduce the beta amyloid damage on PC12 cell model.