T3P® – A Benign Desulfurating Reagent in the Synthesis of Isothiocyanates
2017; Thieme Medical Publishers (Germany); Volume: 50; Issue: 05 Linguagem: Inglês
10.1055/s-0036-1591842
ISSN1437-210X
AutoresTadeusz Gajda, Łukasz Janczewski, Anna Gajda, Sebastian Frankowski, Tomasz M. Goszczyński,
Tópico(s)Chemical Synthesis and Reactions
ResumoA number of alkyl, aryl and bifunctional isothiocyanates are obtained in moderate to high yields (41–94%) in a two-step, one-pot reaction of the parent primary amines or their salts with carbon disulfide, followed by reaction of the thus formed dithiocarbamates with T3P® (propane phosphonic acid anhydride) as a new and efficient desulfurating agent.
Referência(s)