Highly biocompatible BSA-MnO2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy
2017; Elsevier BV; Volume: 29; Issue: 11 Linguagem: Inglês
10.1016/j.cclet.2017.12.004
ISSN1878-5964
AutoresYuzhen Wang, Yujun Song, Guixian Zhu, Dechen Zhang, Xuewu Liu,
Tópico(s)Gold and Silver Nanoparticles Synthesis and Applications
ResumoMore recently, the biomedical applications of MnO2 in bioanalysis, cell imaging, and drug delivery as a result of their appealing physicochemical properties, have been reported and expanded rapidly. However, research on a near infrared (NIR) photothermal response of MnO2 was ignored. In this work, we reported a facile, one-pot method to synthesis of bovine serum albumin (BSA)-reduced and stabilized MnO2 nanoparticles (BSA-MnO2 NPs) with good aqueous dispersibility and high biocompatibility. And we also showed for the first time that BSA-MnO2 NPs displayed superior NIR photothermal efficiency and photostability which demonstrated as a novel class of photothermal antitumor agent.
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