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Latin-America Pediatric Renal Transplant Registry: 2004-2012 Report.

2014; Wolters Kluwer; Volume: 98; Linguagem: Inglês

10.1097/00007890-201407151-01676

1534-6080

Druck C. Garcia, Ángela Delucchi, Nelson Orta, Medina J. Pestana, Peter Koch, Sara Martins, V. Bittencourt, Rachel S. Rohde, Marta Lidia Monteverde, Alicia Chaparro, Luciana de Santis Feltran, María Daniela Camargo, Marcos Antônio Pitaluga Cunha, B. Shvartsman, M. Veisbich, F. Gesteira, Carlos Jefferson do Nascimento Andrade, Ronaldo de Matos Esmeraldo, R. Carvalho, M. Oliveira, Helena Ramalho, I. Fernandes, L. Prates, Leonardo Carvalho Palma, Vera Maria Santoro Belangero, Vanda Benini, Sérgio Laranjo, Elidamar Nunes de Carvalho Lima, John R.F. Penido, Maria Goretti Moreira Guimarães Penido, Mariana Vide Tavares, Jimena Ferraris, Palacios V. Hevia, P. Rosati, Horacio A. Repetto, Ramóm Exeni, José Florín, Domingo Casadei, K. Mellendez, Danielle da Costa Palácio, Gilbert Madrigal, María Paula Castañeda Sandoval, Reyner Loza Munárriz, wilson jimenez, H. Gálvez, L. Rodriguez, F. Puelma, Avelina Troche, Elsa Reyes, Alexánder Mármol, F. Giron, Brisa Arlin Gómez Arteaga, Edna Venegas‐Montoya, M. Martinez-Pico, W. Higueras, César Liendo, Jaime Manuel Restrepo, L. Calcedo, Félix Socorro, P. Semprum, Marina Scop Medeiros, Montserrat Bosque, Lina María Serna-­Higuita, Pedro Ruiz Salas, Valerio Coronel, Avila Cisneros, Jonathan Arriaga, Ricardo Gastelbondo, N. Medjia, Mário Abbud‐Filho,

Renal Diseases and Glomerulopathies

Aim: Latin-America Pediatric Renal Transplant Registry began in 2003. The objective is to analyze and share the results of pediatric kidney transplantation performed in Latin America. Methods: Data of pediatric renal transplants performed on patients from 43 centers in 14 countries: Argentina, Brasil, Chile, Colombia, Costa Rica, Cuba, Ecuador, Guatemala, Honduras, México, Nicaragua, Paraguay, Perú y Venezuela between January 1st, 2004 and December 31st, 2012 was collected. Results: Data on 2944 renal transplants were obtained. Mean age was 11.4+3.6 years, 57% male. Main etiology were congenital uropathy/vesicoureteral reflux (28%), followed by glomerulopathy (23%), including 326(11%) FSGS, hereditary diseases(14.7%), vascular diseases(3.1%), unknown in 17%. Sixty percent of transplants were performed with deceased donors and initial immunosuppression consisted mainly of tacrolimus (77%), mycophenolic acid(71%), steroids(96%) and induction therapy with anti- IL-2R antibodies (72%)One year graft survival was 97% and 87% (p<0,05), respectively for living donors (LD) and deceased donors (DD). Graft loss incidence was 16%, most frequently caused by (in descending order) acute and chronic rejection, arterial or venous thrombosis, death with functioning kidney and recurrent renal disease. Patient survival at 1 and 3 years was 96% and 95%, respectively. Mortality rate was 4% mainly due to infection and cardiovascular disease. Conclusion: The results are comparable to that of other international centers. Efforts are being made to provide on-line data entry, in order to facilitate reporting, and to supply an exchange of information, among the participating centers, as with other centers in the world.