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High Resolution Esophageal Pressure Topography (HREPT) in Asymptomatic Volunteers. A Comparative Study Between Solid-state and Water-perfused Systems

2015; MedCrave Group; Volume: 2; Issue: 2 Linguagem: Inglês

10.15406/ghoa.2015.02.00033

2373-6372

Zavala-Solares Monica,

Esophageal and GI Pathology

Background and aim:I. HREPT is the most accurate technique for identifying esophageal motility disorders (EMD).II.The Chicago Classification (CC) emerged to diagnose EMD.The CC parameters were obtained using a solid-state high resolution manometry (HRM) system.III.There are few studies comparing HREPT metrics between a solid-state versus waterperfused systems.Aim: To compare the HREPT metrics between both systems in healthy volunteers (HV) Patients and methods:I. Observational, transversal, crossover and comparative study.II. HV underwent two HRM: solid-state and water perfused systems.HV were randomized for the first HRM and one week later the other system.One HRM was performed using a solid-state catheter with 36 pressure sensors and Manoview 2.0 analysis program.Another HRM was performed using a water-perfusion catheter with 22 channels and database Inc.MMS program.III.Ten liquid swallows with 5 cc of water were administered.UES pressure, distal contractile integral (DCI), distal latency (DL), LES basal pressure and integrated relaxation pressure (IRP) were analyzed.IV. Statistical analysis was made with STATA version 11.Non-parametric statistics were used to summarize the data and for comparison between the 2 HRM systems.Results: Twenty HV were included, 14 women, mean age 34 (24-55) years.The pressures in the UES and LES pressures, IRP are lower with the perfusion system (p 0.0064, 0.008 and 0.0061, respectively) and have a faster peristalsis registration with the solid system, (DL p 0.0002).With the CC 2012, the solid state system presented a higher frequency of volunteers with hypotensive peristalsis (p 0.0143). Conclusion:HREPT metrics: UESp, LESp and IRP were significantly lower when the HRM was performed with the water-perfused system.These findings must be considered when CC is used to classify EMD with HRM water-perfused system.