Revisão Acesso aberto Revisado por pares

Systematic overview of neuroanatomical differences in ADHD: Definitive evidence

2017; Taylor & Francis; Volume: 43; Issue: 1 Linguagem: Inglês

10.1080/87565641.2017.1414821

ISSN

8756-5641

Autores

Bruno Bastos Vieira de Melo, Maria João Trigueiro, Pedro Pereira Rodrigues,

Tópico(s)

Genetic Neurodegenerative Diseases

Resumo

Objectives: This article seeks to identify neuroanatomical differences in ADHD through an overview of systematic reviews that report encephalic differences compared to a control group in volume, area, activation likelihood or chemical composition.Methods: We conducted a systematic search using Cochrane guidelines and PRISMA criteria in PubMed, Scopus, Web of Science, Cochrane Database of Systematic Reviews and Database of Abstracts of Reviews of Effects.Results: Results revealed broad encephalic involvement that includes a functional frontal and cingulate hypoactivation and structural differences in corpus callosum, cerebellum and basal nuclei.Conclusions: ADHD symptoms might be due to a multi-network unbalanced functioning hypothesis.

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