A fluorescent activatable probe for imaging intracellular Mg 2+
2017; Royal Society of Chemistry; Volume: 16; Issue: 2 Linguagem: Inglês
10.1039/c7ob02965a
ISSN1477-0539
AutoresRyan Treadwell, Fabio De Moliner, Ramon Subirós‐Funosas, Toby W. Hurd, Kirsten Knox, Marc Vendrell,
Tópico(s)Supramolecular Chemistry and Complexes
ResumoAn activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg2+ without interference from Ca2+ is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg2+ due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core.
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