CD103+CD11b+ mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin
2017; Elsevier BV; Volume: 11; Issue: 3 Linguagem: Inglês
10.1038/mi.2017.105
ISSN1935-3456
AutoresAdriana Flores‐Langarica, Katarzyna M. Luda, Emma K. Persson, Charlotte N. Cook, Saeeda Bobat, Jennifer L. Marshall, Madelene W. Dahlgren, Karin Hägerbrand, Kai‐Michael Toellner, Margaret Goodall, David R. Withers, Ian R. Henderson, Bengt Johansson Lindbom, Adam F. Cunningham, William W. Agace,
Tópico(s)Immune Response and Inflammation
ResumoAntibody responses induced at mucosal and nonmucosal sites demonstrate a significant level of autonomy. Here, we demonstrate a key role for mucosal interferon regulatory factor-4 (IRF4)-dependent CD103
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