Portal de Periódicos da CAPES

Nanochannels Photoelectrochemical Biosensor

2017; American Chemical Society; Volume: 90; Issue: 3 Linguagem: Inglês

10.1021/acs.analchem.7b04862

1520-6882

Nan Zhang, Yi‐Fan Ruan, Libin Zhang, Weiwei Zhao, Jing‐Juan Xu, Hong‐Yuan Chen,

Anodic Oxide Films and Nanostructures

Nanochannels have brought new opportunities for biosensor development. Herein, we present the novel concept of a nanochannels photoelectrochemical (PEC) biosensor based on the integration of a unique CuxO-nanopyramid-islands (NPIs) photocathode, an anodic aluminum oxide (AAO) membrane, and alkaline phosphatase (ALP) catalytic chemistry. The CuxO-NPIs photocathode possesses good performance, and further assembly with AAO yields a designed architecture composed of vertically aligned, highly ordered nanoarrays on top of the CuxO-NPIs film. After biocatalytic precipitation (BCP) was stimulated within the channels, the biosensor was used for the successful detection of ALP activity. This study has not only provided a novel paradigm for an unconventional nanochannels PEC biosensor, which can be used for general bioanalytical purposes, but also indicated that the new concept of nanochannel-semiconductor heterostructures is a step toward innovative biomedical applications.