Protective Effect of Cyathula Prostrata Extract on Alloxan Induced Diabetes Mellitus in Rats
2012; RELX Group (Netherlands); Linguagem: Inglês
ISSN
1556-5068
AutoresK. Gurusamy, Mani Kavitha, K. Priya, J. Kowshik,
Tópico(s)Natural Products and Biological Research
ResumoThe present study was made to evaluate the antidiabetic effect of Cyathula prostrata extract in alloxan monohydrate induced diabetic rats. Changes in biochemical parameters like aspartate transaminase (AST), alanine transaminase (ALT), lactate dehydrogenase (LDH), and alkaline phosphatase (ALP) in liver, glucose and cholesterol in serum were studied and found to be increased in alloxan induced diabetic rats. This condition was reversed by the oral administration of Methanolic Extract of Cyathula Prostrata (MECP) in Group 3 rats. Our results suggest that the extract possesses a potent medicinal agent for the treatment of diabetes mellitus.
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