Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis
2018; American Association for the Advancement of Science; Volume: 10; Issue: 422 Linguagem: Inglês
10.1126/scitranslmed.aan3128
ISSN1946-6242
AutoresDuncan Richards, Louise Cookson, Sharon V. Barton, Lia Liefaard, Thirusha Lane, David F. Hutt, James M. Ritter, Marianna Fontana, James Moon, Julian D. Gillmore, Ashutosh D. Wechalekar, Philip N. Hawkins, Mark B. Pepys,
Tópico(s)Neuroendocrine Tumor Research Advances
ResumoRepeat cycles of miridesap, to deplete circulating serum amyloid P component (SAP), followed by the anti-SAP antibody, dezamizumab, cleared visceral amyloid deposits in patients with systemic amyloidosis.
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