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Immune-Related Adverse Events Associated with Immune Checkpoint Blockade

2018; Massachusetts Medical Society; Volume: 378; Issue: 2 Linguagem: Inglês

10.1056/nejmra1703481

1533-4406

Michael A. Postow, Robert Sidlow, Matthew D. Hellmann,

Immune Cell Function and Interaction

The wide range of immune-related adverse effects associated with immune checkpoint blockade can complicate this effective therapy and limit its use in patients with cancer. This review surveys the adverse effects and their management.