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A red-emitting fluorescent probe for hydrogen sulfide in living cells with a large Stokes shift

2018; Royal Society of Chemistry; Volume: 16; Issue: 7 Linguagem: Inglês

10.1039/c7ob02641b

1477-0539

Lei Yang, Yuanan Su, Zhankui Sha, Yani Geng, Fengpei Qi, Xiangzhi Song,

Luminescence and Fluorescent Materials

A red-emitting fluorescent probe was developed for the sensitive and selective detection of H2S. Upon treatment with H2S, this probe exhibited a remarkable fluorescence enhancement (10 fold) with a large Stokes shift (125 nm). The detection limit of this probe was as low as 5.7 nM based on S/N = 3. The application of this probe in the detection of intracellular H2S in living cells is successfully demonstrated.